Cannabis plant in it’s cca 28 million years of evolution found popularity in fairly early stages of our civilization’s development, attracting attention of Asian cultures and travelled west to spread on. It was highly valued for it’s fiber and used often in construction and production of clothing as well as ropes and fishing nets. With lower levels of cannabinoids content, people more appreciated the plants value as a resource than otherwise. After identification of male/female traits and observation of cultivation impact on the crops depending on manipulation of removing males from the population, they also discovered the medicinal properties of female flowers. One of the main therapeutical applications were pain suppression, sleep control and mental illness treatments, meaning Chinese people went fast from observing slight mental effects to wide application in Chinese traditional herbal medicine, lasting for about 1800 years. Cannabis spread to other cultures and continents, being used more or less in the same manner and for similar purposes, showing common point of view among different cultures.