The newly developed Covid-19 vaccines have been a key example for the recent success of mRNA technology, but not everyone may know that mRNA therapeutic products have been studied, around the world, for decades.
The intrinsic instability of mRNA plus the difficulties in putting such molecules inside an adequate protective “drop” have always been the major challenges for such products’ perspectives. Thus, at the beginning of the 1990s, it was almost impossible to inject an mRNA-based product into patients and expect it to work properly. Today, such products have already been successfully administered to millions of people all over the world and are opening other doors for cancer therapies, HIV, infectious diseases and genetic disorders.